Population-based epidemiology of trauma, surgical outcomes, and health systems performance — spanning TBI, vascular injury, VTE, pediatric trauma, and beyond.
My work evaluates data at all levels, including single-center evaluation to large administrative databases. Large-scale data include the California HCAI patient discharge database, the ACS Trauma Quality Improvement Program, and AHRQ HCUP sources. I have significant experience in applying epidemiologic principles for the design of observational studies and randomized trials at single- and multi-institutional settings. My emphasis is always to develop the most appropriate and rigorous study and the selection of appropriate methods to address any question.
Analytic methods across my published work include competing risks survival analysis, Cox proportional hazards modeling, multilevel logistic regression, propensity score matching, Poisson regression for trend analysis, and machine learning clustering approaches. R and Stata serve as my primary platforms. A consistent thread across projects is translating epidemiologic findings into actionable clinical and systems-level recommendations.
Coauthorship network derived from PubMed · node size = papers shared with me · colour = detected research community · hover a node to trace their direct collaborators.
Management and outcomes of TBI across the severity spectrum — including anticoagulation effects, ICP monitoring versus ventriculostomy, mild TBI triage, and pediatric-specific considerations. Emphasis on identifying modifiable risk factors and right-sizing resource utilization.
Prophylaxis, risk stratification, and outcomes for post-traumatic DVT and PE. Published work includes randomized trials, competing risks analyses, and evaluations of anticoagulant agents, plasma resuscitation, cannabis, and aspirin as modifiers of VTE risk.
Epidemiology and outcomes of extremity vascular injury, penetrating thoracic trauma, and surgical complications in children. Emphasis on the role of trauma center designation, case volume, and system-level factors in driving variability in outcomes.
Financial vulnerability of trauma centers, true cost of trauma care, fragmentation of care after discharge, and the impact of organizational structure on quality. Used large statewide and national administrative datasets to identify system-level opportunities for improvement.
Comorbidity burden as a driver of trauma outcomes — including novel risk-scoring approaches, the role of anticoagulants and antiplatelets in older injured patients, sarcopenia as a mortality predictor, and substance use in aging trauma populations.
Peripheral and thoracic vascular injury management, REBOA and partial REBOA physiology, and limb salvage outcomes. Collaborative work spanning single-institution registries, multicenter studies, and swine hemorrhagic shock models.
Based on articles retrieved from PubMed · Richard Y. Calvo · Scripps Mercy Hospital